Combination Chemotherapy in Lymphosarcoma and Reticulum Cell Sarcoma

Combination chemotherapy in lymphosarcoma and reticulum cell sarcoma.

T HE CHEMOTHERAPEUTIC MANAGEMENT of patients with lymphosarcoma and reticulum cell sarcoma has usually been accomplished with single agents. The alkylating agents cyclophosphamide and chlorambucil have been widely used,’3 while of the ymca alkaloids, vincristine appears most effective.46 The efficacy of corticosteroids in varying dosages was shown several times.7’8 The remission induction rates...

[results of Radiation Treatment of Reticulum Cell Sarcoma, Lymphosarcoma, Giant Follicular Lymphoma and Hodgkin's Disease].

Ocular reticulum cell sarcoma.

Although rare, ocular reticulum cell sarcoma presents a recognisable clinical pattern, as confirmed by 3 new cases. Typical patients, in their sixth and seventh decades, initially complain of gradual visual loss. Examination reveals 'uveitis' with prominent vitreous debris and/or chorioretinal infiltrative lesions. Topical steroid and mydriatic therapy is ineffective. Reticulum cell sarcoma in ...

Reticulum-cell sarcoma in infancy.

In August, 1948, at the age of 1 year, this baby girl was admitted to the surgical wards of the Royal Hospital for Sick Children, Glasgow, with a red, hot and painful swelling of the left leg of 10 days' duration. The temperature was 1010 F. and the white blood count 8,000. A diagnosis of haematogenous osteitis was made, the limb was immobilized, and, after removing venous blood for culture, pe...

Immunoglobulin-production and surface-bound immunoglobulins in chronic lymphocytic leukemia, lymphosarcoma, and so-called reticulum cell sarcoma.

Conventional light and electron microscopic methods do not allow a differentiation of Tand B-cells. A clasdficntion of neoplastic lymphatic cells into one of these subpopulations is therefore impossible with common morphological methods. It was not until specific cell funktions, i e. immunoglobulin(IG)-production and the formation of surface-Ig(S-Ig)-receptors, were demonstrable that one could ...